Mather Khan | Plant Biotechnology | Excellence in Plant Research

Dr. Mather Khan | Plant Biotechnology | Excellence in Plant Research

University of Missouri | United States

Dr. Mather A. Khan is a Plant Molecular Biologist with over a decade of expertise in metal homeostasis, nutrient regulation, and abiotic stress responses. His research integrates yeast systems, high-throughput molecular screening, and multi-omics approaches to unravel plant-environment interactions. He has significantly advanced knowledge of iron sensing, transporter biology, and crop biofortification strategies. Dr. Khan has successfully led independent and collaborative research programs across renowned institutions in the USA, Germany, and India. His work emphasizes sustainable agriculture, food security, and plant stress biology, resulting in numerous high-impact publications and recognition as a leader in molecular plant sciences.

Author Profiles

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Education

Dr. Khan earned his Ph.D. in Biotechnology from Hamdard University, where he focused on Fusarium wilt resistance in chickpea through microbial and nutrient-based approaches. He completed his M.Sc. in Biotechnology from Barkatullah University, conducting cancer-related research at CNCI Kolkata, and obtained his B.Sc. in Biosciences from the University of Calcutta. To expand his leadership and communication skills, he pursued the prestigious PTLS Certificate Program at the University of Missouri, designed to prepare scientists for team-driven research environments. His multidisciplinary academic training provided a strong foundation in molecular biology, biotechnology, and plant sciences, shaping his career in plant stress research.

Professional Experience 

Dr. Khan has held prominent research positions at leading universities worldwide. As Scientist at the University of Missouri, he advances integrative approaches to decode iron sensing in plants and engineer next-generation transporters for crop nutrition. At Heinrich Heine University, Germany, he spearheaded studies on iron homeostasis and mentored young researchers while contributing to CEPLAS initiatives on crop biofortification. Earlier, as Research Scientist and Postdoctoral Fellow at Missouri, he developed large transcription factor libraries, optimized high-throughput Y1H systems, and pioneered single-cell proteomics. His career demonstrates consistent leadership in innovation, collaboration, and mentoring within plant molecular biology and sustainable agricultural research.

Awards and Recognition 

Dr. Khan’s contributions to plant molecular biology have been widely recognized. He has served as a Panelist for the U.S. National Science Foundation’s Division of Biological Infrastructure, reflecting his standing in the international scientific community. His selection as a Member of the German Cluster of Excellence on Plant Sciences further highlights his expertise. He has been honored as a Plantae Fellow by the American Society of Plant Biologists and received multiple institutional awards, including the Douglas D. Randall Young Scientists Development Fund and Life Sciences Center Travel Award. His early academic excellence was recognized through national science awards in India.

Research Skills

Dr. Khan brings a diverse technical portfolio spanning molecular biology, synthetic biology, plant physiology, and multi-omics integration. His expertise includes CRISPR-based genome engineering, advanced cloning, and design of custom expression vectors. He has developed high-throughput yeast one- and two-hybrid platforms for protein interaction discovery, alongside proteomic, transcriptomic, and metabolomic profiling techniques. His work incorporates live-cell confocal imaging, hydroponic plant systems, and elemental analysis to study plant stress and nutrient responses. Equally strong in computational biology, he applies R and Python for omics integration and data visualization. This breadth enables him to design innovative, interdisciplinary solutions for sustainable agricultural development.

Publications

Ngigi, M., Khan, M., Remus, R., Gupta, S.K., Bauer, P., & Blaby-Haas, C. (2025). “Age-dependent differential iron deficiency responses of rosette leaves during reproductive stages in Arabidopsis thaliana” in Journal of Experimental Botany.

Sinha, R., Zandalinas, S.I., Peláez-Vico, M.Á., Ghani, A., Khan, M.A., Induri, S.P., Bereimipour, A., Ghandour, T., Ogden, A., Huang, S.-S.C., et al. (2025). “bHLH35 mediates specificity in plant responses to multiple stress conditions” in Preprint.

Ngigi, M., Khan, M., Remus, R., Gupta, S.K., & Bauer, P. (2024). “Age-dependent differential iron deficiency responses of rosette leaves during reproductive stages in Arabidopsis thaliana” in Preprint.

Lichtblau, D.M., Baby, D., Khan, M., Trofimov, K., Ari, Y., Schwarz, B., & Bauer, P. (2023). “The small iron-deficiency-induced protein OLIVIA and its relation to the bHLH transcription factor POPEYE” in Preprint.

Nguyen, N.T., Khan, M.A., Castro–Guerrero, N.A., Chia, J.-C., Vatamaniuk, O.K., Mari, S., Jurisson, S.S., & Mendoza-Cozatl, D.G. (2022). “Iron availability within the leaf vasculature determines the magnitude of iron deficiency responses in source and sink tissues in Arabidopsis” in Plant and Cell Physiology.

McInturf, S.A., Khan, M.A., Gokul, A., Castro-Guerrero, N.A., Höhner, R., Li, J., Marjault, H.-B., Fichman, Y., Kunz, H.-H., Goggin, F.L., et al. (2022). “Cadmium interference with iron sensing reveals transcriptional programs sensitive and insensitive to reactive oxygen species” in Journal of Experimental Botany.

Ahmed, J., Jha, S.G., Ameen, G., Buer, B., Fahlgren, N., Farmer, A., Huang, S.-S.C., Bartley, L., Bassel, G.W., Bergmann, D.C., Khan, M.A., et al. (2021). “Vision, challenges and opportunities for a Plant Cell Atlas” in OpenAlex.

Conclusion

Dr. Mather A. Khan exemplifies the integration of molecular plant biology with applied agricultural innovation. His scientific journey reflects consistent advancement of knowledge in nutrient regulation, stress adaptation, and biofortification. With proven ability to lead high-impact projects, mentor researchers, and secure competitive funding, he continues to contribute to global food security and sustainable development goals. His interdisciplinary approach bridges molecular systems with real-world crop improvement strategies. Supported by international recognition, extensive publications, and impactful collaborations, Dr. Khan stands as a distinguished researcher committed to advancing plant science for future agricultural resilience and nutritional improvement on a global scale.